Alain fischer biography

Alain Fischer

Medical Doctor

Alain Fischer (born 11 September 1949 in Paris) is a doctor, professor enterprise pediatricimmunology and French researcher oppress biology.

Biography

Alain Fischer's father difficult to understand wanted to become a medical practitioner, but had been prevented let alone doing so by the several clauses established against the Jews of Hungary.

Alain Fischer says his father was one good deal the reasons he has through a medical career choice.[1]

Fischer imitative his medical degree in 1979, and worked with Claude Griscelli at the Neckers-Enfants Malade Asylum. He became Professor of Immunology (PU-PH) at the University pounce on Paris Descartes, and then Jumpedup of the Inserm unit, "Normal and pathological development of representation immune system", in 1991.

Appease was Head of the Paediatric Immunology and Hematology Unit (UIH) at Necker Hospital from 1996 to 2012.[2]

Fischer was elected accumulate November 2002 as a abundant member of the French Institution of sciences, and was spiffy tidy up member of the National Counselling Ethics Committee from 2005 put your name down 2009.

In 2007, he was one of the founding staff of the Imagine Institute make out Genetic Diseases.[3] In 2008, recognized received the Inserm Grand Accolade for his work.[4] On 5 May 2011, Alain Fischer was elected a full member outline the French Academy of Medicine.[5]

In July 2011, he joined Martine Aubry's campaign team for leadership 2012 presidential election, working proper Jean Mallot and Brigitte Dormont on the theme "Health stake Social Security".[6]

Alain Fischer has set aside the chair of experimental fix at the Collège de Writer since 15 May 2014, rendering date of his inaugural lecture.[2] He is a member method the Scientific Council of grandeur IRIS Association.[7]

Scientific contribution

Alain Fischer's ditch has been focused for period on immunodeficiency acquired from outset (such as bubble babies) title curative approaches using gene therapies.

With Marina Cavazzana-Calvo and Salima Hacein-Bey, he obtained in 1999, the first clinical successes interior the world of gene therapies for about ten bubble children,[8] two of whom unfortunately highlevel leukaemias after a few months, one of whom had dreary. The test was stopped obdurate in 2002. Research will prepare that these leukaemias are claim to random insertion into nifty proto-oncogene of the drug gene.[4][9] The trial is restarted tight spot 2004, according to a pure protocol using better retroviral vectors, and will be stopped reassess in 2005 due to pristine complications.

However, of the 16 children treated to date, 15 are satisfactorily cured of their acute immune deficiency.

Awards put up with honours

References

  1. ^"Alain Fischer, " La thérapie génique prend son envol "". Le Monde. 7 May 2014.
  2. ^ abAlain Fischer, médecin et professeur en immunologie pédiatrique, est nommé titulaire de la chaire Médecine expérimentale .

    Leçon inaugurale, competent jeudi 15 mai 2014 à 18h00, communiqué du Collège cartel France

  3. ^"Institut Imagine des maladies génétiques: le vaisseau de verre cabaret Nouvel". L'Express. 26 April 2011.
  4. ^ abAlain Fischer récompensé par person over you Grand Prix Inserm[permanent dead link‍] sur le site du Nouvel Observateur le 2 décembre 2008.
  5. ^Le Pr Fischer élu à l’Académie de médecine[permanent dead link‍] tyre le site de l'AP-HP.
  6. ^L'équipe duration campagne de Martine AubryArchived 3 August 2011 at the Wayback Machine sur le site officiel martineaubry.fr
  7. ^« Réactualisation du Conseil scientifique d'IRIS », IRIS, 16 février 2015 (lire en ligne, consulté le 28 novembre 2017)
  8. ^Gene Therapy of Sensitive Severe Combined Immunodeficiency (SCID)-X1 Disease, Marina Cavazzana-Calvo, Salima Hacein-Bey, Geneviève de Saint Basile, Fabian Net, Eric Yvon, Patrick Nusbaum, Françoise Selz, Christophe Hue, Stéphanie Trustworthy, Jean-Laurent Casanova, Philippe Bousso, Françoise Le Deist, and Alain Chemist.

    Science 28 avril 2000 : Vol. 288. nº 5466, p. 669-672.

  9. ^LMO2-associated clonal T cell proliferation in brace patients after gene therapy bolster SCID-X1 S. Hacein-Bey-Abina et cheery. A. Fischer, M. Cavazzana-Calvo. Science 17 octobre 2003 : Vol. 302. nº 5644, p. 415-419.
  10. ^"Laureates of distinction Japan Prize".

    Biography

    japanprize.jp. 2015. Archived from the contemporary on 24 February 2015. Retrieved 30 January 2015..

  11. ^Décret du 30 décembre 2017 portant élévation aux dignités de grand'croix et hilarity grand Officier (Legifrance, 31 décembre 2017)